Mechanism of Action

Testosterone undecanoate binds to androgen receptors in muscle, bone, and the central nervous system. This activates biological processes that support protein synthesis, muscle growth, fat metabolism, and secondary male sexual characteristics. The anabolic effects improve muscle mass, strength, and overall body composition.

Indications

• Treatment of hypogonadism in adult males with low testosterone levels, which may present as fatigue, reduced libido, or muscle loss.

• Occasionally used for delayed puberty in men or specific conditions in women, though less common.

Contraindications

Avoid use in individuals with:

• Hypersensitivity to testosterone or components of the formulation

• Prostate or breast cancer in men

• Severe liver disease

• Serious cardiovascular disorders

Precautions

• Monitor for side effects such as polycythemia, sleep apnea exacerbation, or mood changes.

• Regular hormone level assessments are important.

• Consider cardiovascular risks in older adults or those with pre-existing health conditions.

Drug Interactions

• May interact with anticoagulants, corticosteroids, and some antidiabetic medications.

• Disclose all medications, supplements, and herbal products to a healthcare provider before starting therapy.

Dosage

• Individualized based on clinical response and testosterone levels.

• Typical starting regimen: 40 mg orally, twice daily with food.

• Maintenance dose often ranges from 40 to 120 mg daily, split into two doses, adjusted according to serum testosterone and therapeutic response.

Storage

• Store in a dark, dry place at room temperature.

• Do not refrigerate.

• Keep out of reach of children.

Prescription Requirement

This medicine must be used only under medical supervision.

Regulatory and Safety Notes

• Complies with relevant regulatory guidelines and is GMP-certified.

• In case of overdose, seek immediate medical attention.

• Report any adverse reactions to a healthcare provider.